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R&D PROFILE

Delivering Innovative Therapies for Patients
Accelerating the Transition from "New in China" to "New Globally"
Sino Biopharmaceutical Limited adheres to the vision of "Focusing on Innovation, Serving Patients, and Becoming a World-Leading Pharmaceutical Enterprise". For many years, it has continuously increased R&D investment to build an internationally competitive innovation system, and was selected as one of the "Top 3 in China's Pharmaceutical Innovation" by the China Pharmaceutical Innovation and Investment Index (China PIII).
The company focuses on four major therapeutic areas: neoplasm, liver disease, respiratory, and surgery/analgesia, forming an innovative drug R&D pipeline that covers multiple cutting-edge targets. It continues to build a competitive drug R&D platform, with investment in innovative drug R&D accounting for over 80% of total R&D spending, and its innovation pipeline ranks among the top globally. Its core enterprises, such as CTTQ Pharma and Beijing Tide Pharmaceutical, have undertaken more than 80 national and provincial/ministerial-level scientific research projects and have won major science and technology awards such as the "China Patent Gold Award" and the "National Science and Technology Progress Award".
The company has established multiple R&D and innovation centers in Beijing, Shanghai, Nanjing, Lianyungang, as well as in Europe and North America, with a global R&D team of over 2,900 people. We adhere to the concept of openness and win-win cooperation, striving to become a world-leading pharmaceutical enterprise. Through measures such as in-house innovation, major business development (BD) deals, international cooperation, and M&A, we actively supplement our innovation pipeline and technology platforms. At the same time, we connect extensively with renowned research institutions and scientific institutes at home and abroad, gathering global innovation resources to expand our international influence.
By the end of 2025, the company will have a cumulative total of 21 innovative products approved for marketing; in the next three years, more than ten innovative products are expected to enter the marketing stage. We look forward to bringing more and better medication options to patients as an increasing number of high-quality products enter their intensive harvest period, warming more lives with healthy technology.
The company focuses on four major therapeutic areas: neoplasm, liver disease, respiratory, and surgery/analgesia, forming an innovative drug R&D pipeline that covers multiple cutting-edge targets. It continues to build a competitive drug R&D platform, with investment in innovative drug R&D accounting for over 80% of total R&D spending, and its innovation pipeline ranks among the top globally. Its core enterprises, such as CTTQ Pharma and Beijing Tide Pharmaceutical, have undertaken more than 80 national and provincial/ministerial-level scientific research projects and have won major science and technology awards such as the "China Patent Gold Award" and the "National Science and Technology Progress Award".
The company has established multiple R&D and innovation centers in Beijing, Shanghai, Nanjing, Lianyungang, as well as in Europe and North America, with a global R&D team of over 2,900 people. We adhere to the concept of openness and win-win cooperation, striving to become a world-leading pharmaceutical enterprise. Through measures such as in-house innovation, major business development (BD) deals, international cooperation, and M&A, we actively supplement our innovation pipeline and technology platforms. At the same time, we connect extensively with renowned research institutions and scientific institutes at home and abroad, gathering global innovation resources to expand our international influence.
By the end of 2025, the company will have a cumulative total of 21 innovative products approved for marketing; in the next three years, more than ten innovative products are expected to enter the marketing stage. We look forward to bringing more and better medication options to patients as an increasing number of high-quality products enter their intensive harvest period, warming more lives with healthy technology.
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0 %+R&D Personnel Hold a Master's Degree or Higher
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0 +Innovative drug projects in the pipeline
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0 +National Science and Technology Major Projects for
"Innovative Drug Research and Development" undertaken -
0 +Patents Granted Cumulatively
TECHNOLOGY INNOVATION
PIPELINE PROGRESS
This section provides a comprehensive overview of key updates on projects under development across member companies of Sino Biopharmaceutical (01177.HK), covering key stages including clinical research and marketing applications for innovative drugs and biosimilars. It fully showcases the R&D pipeline progress of Sino Biopharmaceutical and provides clear and detailed R&D information for investors, partners, and industry peers.
116
All
38
Preclinical
30
Phase I
22
Phase II
22
Phase III/Pivotal Clinical
4
Marketing Application
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Oncology
-
Respiratory
Autoimmune -
Liver
Cardiometabolic -
Surgery
Analgesic
- Innovative Drug
- Biosimilar
- Phase I
- Phase II
- Phase III
- Marketing Application
- Preclinical
- Clinical
- Pivotal Clinical
- Marketing Application
| Product | Target/Mechanism of Action | Indication | IIIIIIMarketing Application |
|---|---|---|---|
| TQB3616 | CDK2/4/6 inhibitor | HR+/HER2- breast cancer | |
| TQ05105 | JAK/ROCK inhibitor | Myelofibrosis, graft versus host disease, hemophagocytic syndrome | |
| AL2846 | AXL/MET tyrosine kinase inhibitor | Non-small cell lung cancer, differentiated thyroid cancer | |
| TQB3454 | IDH1 inhibitor | Advanced biliary tract cancer with IDH1 mutation | |
| TQB2102 | HER2 bispecific ADC | Breast cancer, non-small cell lung cancer, biliary tract cancer, colorectal cancer, gastric cancer, and other advanced malignant neoplasm | |
| M701 | CD3/EpCAM bispecific antibody | Malignant ascites, malignant pleural effusion | |
| TQB3473 | SYK inhibitor | Primary immune thrombocytopenia | |
| FHND9041 | EGFR inhibitor (3rd generation) | Non-small cell lung cancer | |
| TQB3909 | BCL-2 inhibitor | Chronic lymphocytic leukaemia/small lymphocytic lymphoma, acute myeloid leukaemia, acute lymphocytic leukaemia, etc. | |
| LM-108 | CCR8 monoclonal antibody | Advanced malignant neoplasm | |
| TQB2868 | Anti-PD-1/TGF-β bifunctional fusion protein | Pancreas cancer | |
| TQB2930 | HER2 bispecific antibody | Breast cancer, gastric cancer | |
| TQB2916 | CD40 agonistic monoclonal antibody | Advanced malignant neoplasm | |
| TQB2928 | CD47 monoclonal antibody | Bone sarcoma | |
| TQB3702 | BTK inhibitor | Relapsed/refractory advanced hematologic malignancies | |
| TQB3617 | BET inhibitor | Myelofibrosis | |
| TQB3915 | Selective estrogen receptor covalent antagonist (SERCA) | HR+/HER2- breast cancer | |
| TQB2825 | CD20/CD3 bispecific antibody | Follicular lymphoma, diffuse large B-cell lymphoma, mantle cell lymphoma | |
| FHND6091 | Proteasome inhibitor | Multiple myeloma, biliary tract cancer, lupus erythematosus | |
| FHND5071 | RET inhibitor | Solid tumor | |
| NTQ1062 | AKT inhibitor | Solid tumor | |
| TQB3720 | Androgen receptor (AR) antagonist | Prostate cancer | |
| TQB2103 | Claudin18.2 ADC | Advanced malignant neoplasm | |
| TQB2934 | BCMA/CD3 bispecific antibody | Multiple myeloma | |
| TQB3912 | AKT inhibitor | Advanced malignant neoplasm | |
| TQB2922 | EGFR/cMET bispecific antibody | Advanced malignant neoplasm | |
| TQB3006 | SOS1 inhibitor | Advanced malignant neoplasm | |
| TQB3107 | XPO1 inhibitor | Lymphoma, leukaemia, and various solid tumors | |
| TQB3117 | ATM inhibitor | Advanced malignant neoplasm | |
| TQB3911 | BCR-ABL1 tyrosine kinase inhibitor | Hematological malignancy | |
| TQB3002 | EGFR inhibitor (4th generation) | Advanced malignant neoplasm | |
| TQB2029 | GPRC5D/CD3 bispecific antibody | Multiple myeloma | |
| TQB2252 | PD-1/LAG-3 combination | Advanced malignant neoplasm | |
| TCC1727 | Selective ATR inhibitor | Advanced malignant neoplasm | |
| NTQ3617 | MAT2A inhibitor | Advanced malignant neoplasm | |
| TQH2722 | IL-4Rα monoclonal antibody | Chronic sinusitis with/without nasal polyps, atopic dermatitis, seasonal allergic rhinitis | |
| TQC2731 | TSLP monoclonal antibody | Severe asthma, chronic sinusitis with nasal polyps, chronic obstructive pulmonary disease (COPD) | |
| TQC3721 | PDE3/4 inhibitor | Chronic obstructive pulmonary disease (COPD) | |
| TQC2938 | ST2 monoclonal antibody | Asthma, chronic obstructive pulmonary disease (COPD) | |
| TDI01 | ROCK2 inhibitor | Idiopathic pulmonary fibrosis (IPF), graft-versus-host disease (GVHD) | |
| CPX102 | Type III interferon (IL-29) | Respiratory syncytial virus (RSV) infection | |
| TCR1672 | P2X3 antagonist | Refractory chronic cough | |
| TQC3927 | MABA dual target | Chronic obstructive pulmonary disease (COPD) | |
| TQD3524 | Polymyxin E2 | Carbapenem-resistant organism (CRO) infection | |
| TQD3606 | Meropenem and avibactam sodium | Carbapenem-resistant organism (CRO) infection | |
| TQC3301 | Budesonide inhalation spray | Asthma | |
| Lanifibranor | Pan-PPAR agonist | Metabolic dysfunction-associated steatohepatitis (MASH) | |
| TQA2225 | FGF21 fusion protein | Metabolic dysfunction-associated steatohepatitis (MASH) | |
| TQ-A3334 | TLR-7 agonist | Hepatitis B | |
| TQA3810 | TLR-8 agonist | Hepatitis B | |
| TQA3605 | HBV capsid assembly modulator (CAM) | Hepatitis B | |
| TQA3038 | siRNA | Hepatitis B | |
| CPX101 | GIPR antagonist/GLP-1R agonist | Weight loss | |
| PL-5 | Antimicrobial peptide | Secondary wound infection | |
| QP001 | Meloxicam injection (COX-2 inhibitor) | Postoperative analgesia in adults | |
| Naldemedine | Peripherally acting μ-opioid receptor antagonist | Opioid-induced constipation | |
| TRD205 | AT2R antagonist | Neuropathic pain | |
| TRD303 | Ropivacaine extended-release solution (local anesthetic) | Postoperative analgesia | |
| YMP | Dexmedetomidine transdermal patch (α2-adrenergic receptor agonist) | Perioperative insomnia |
| Product | Indication | PreclinicalClinicalPivotal ClinicalMarketing Application |
|---|---|---|
| Degarelix acetate for injection | Advanced prostate cancer | |
| Enzalutamide soft capsules | Prostate cancer | |
| Ruxolitinib tablets | Myelofibrosis | |
| Ibrutinib capsules | Mantle cell lymphoma, chronic lymphocytic leukaemia, etc. | |
| Pamidronate disodium injection | Neoplasm bone metastasis | |
| Apalutamide tablets | Prostate cancer | |
| Nelarabine injection | Lymphocytic leukaemia, lymphoma | |
| Abiraterone acetate tablets (II) | Prostate cancer | |
| Daratumumab injection | Multiple myeloma | |
| Netupitant and palonosetron capsules | Chemotherapy-induced vomiting | |
| Ixazomib citrate capsules | Multiple myeloma | |
| Relugolix tablets | Prostate cancer | |
| Chidamide tablets | Breast cancer, diffuse large B-cell lymphoma, etc. | |
| Tedizolid phosphate for injection | Antibacterial | |
| Umeclidinium and vilanterol inhalation powder | Chronic obstructive pulmonary disease (COPD) | |
| Tiotropium bromide inhalation powder | Chronic obstructive pulmonary disease (COPD) | |
| Amphotericin B liposome for injection | Deep fungal infection | |
| Posaconazole injection | Antifungal | |
| Procaterol hydrochloride granules | Bronchodilator | |
| Arformoterol tartrate solution for nebulization | Chronic obstructive pulmonary disease (COPD) | |
| Bromhexine hydrochloride solution for inhalation | Patients with difficulty expectorating sputum due to chronic bronchitis, asthma, etc. | |
| Mepolizumab injection | Asthma, chronic sinusitis with nasal polyps | |
| Delamanid tablets | Multidrug-resistant pulmonary tuberculosis | |
| Fluticasone furoate and vilanterol inhalation powder | Asthma, chronic obstructive pulmonary disease (COPD) | |
| Salmeterol and fluticasone inhalation powder | Asthma | |
| Beraprost sodium sustained-release tablets | Primary pulmonary arterial hypertension, pulmonary arterial hypertension complicated by scleroderma | |
| Obeticholic acid tablets | Primary biliary cholangitis | |
| Saxagliptin and metformin hydrochloride extended-release tablets | Type 2 diabetes mellitus | |
| Empagliflozin and metformin hydrochloride extended-release tablets | Type 2 diabetes mellitus | |
| Insulin degludec injection | Type 2 diabetes mellitus | |
| Semaglutide injection | Type 2 diabetes mellitus, weight loss | |
| Insulin degludec and liraglutide injection | Type 2 diabetes mellitus | |
| Empagliflozin, linagliptin, and metformin hydrochloride extended-release tablets | Type 2 diabetes mellitus | |
| Recombinant human coagulation factor VIIa for injection | Hemorrhagic disorder | |
| Eldecalcitol soft capsules | Osteoporosis | |
| Flurbiprofen patch (2nd generation) | Analgesia and anti-inflammation for the following diseases and symptoms: osteoarthritis, scapulohumeral periarthritis, myalgia, swelling and pain due to trauma, etc. | |
| Mirogabalin tablets | Neuralgia | |
| Methocarbamol injection | Adjunctive therapy for acute musculoskeletal pain or discomfort | |
| Risedronate sodium tablets | Treatment and prevention of osteoporosis in postmenopausal women | |
| Pregabalin extended-release tablets | Diabetic peripheral neuropathic pain (DPNP) | |
| Elagolix sodium tablets | Endometriosis related pain |
No data available
