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R&D PROFILE

Delivering Innovative Therapies for Patients
Accelerating the Transition from "New in China" to "New Globally"
Sino Biopharmaceutical Limited adheres to the vision of "Focusing on Innovation, Serving Patients, and Becoming a World-Leading Pharmaceutical Enterprise". For many years, it has continuously increased R&D investment to build an internationally competitive innovation system, and was selected as one of the "Top 3 in China's Pharmaceutical Innovation" by the China Pharmaceutical Innovation and Investment Index (China PIII).
The company focuses on four major therapeutic areas: neoplasm, liver disease, respiratory, and surgery/analgesia, forming an innovative drug R&D pipeline that covers multiple cutting-edge targets. It continues to build a competitive drug R&D platform, with investment in innovative drug R&D accounting for over 80% of total R&D spending, and its innovation pipeline ranks among the top globally. Its core enterprises, such as CTTQ Pharma and Beijing Tide Pharmaceutical, have undertaken more than 80 national and provincial/ministerial-level scientific research projects and have won major science and technology awards such as the "China Patent Gold Award" and the "National Science and Technology Progress Award".
The company has established multiple R&D and innovation centers in Beijing, Shanghai, Nanjing, Lianyungang, as well as in Europe and North America, with a global R&D team of over 2,900 people. We adhere to the concept of openness and win-win cooperation, striving to become a world-leading pharmaceutical enterprise. Through measures such as in-house innovation, major business development (BD) deals, international cooperation, and M&A, we actively supplement our innovation pipeline and technology platforms. At the same time, we connect extensively with renowned research institutions and scientific institutes at home and abroad, gathering global innovation resources to expand our international influence.
By the end of 2025, the company will have a cumulative total of 21 innovative products approved for marketing; in the next three years, more than ten innovative products are expected to enter the marketing stage. We look forward to bringing more and better medication options to patients as an increasing number of high-quality products enter their intensive harvest period, warming more lives with healthy technology.
The company focuses on four major therapeutic areas: neoplasm, liver disease, respiratory, and surgery/analgesia, forming an innovative drug R&D pipeline that covers multiple cutting-edge targets. It continues to build a competitive drug R&D platform, with investment in innovative drug R&D accounting for over 80% of total R&D spending, and its innovation pipeline ranks among the top globally. Its core enterprises, such as CTTQ Pharma and Beijing Tide Pharmaceutical, have undertaken more than 80 national and provincial/ministerial-level scientific research projects and have won major science and technology awards such as the "China Patent Gold Award" and the "National Science and Technology Progress Award".
The company has established multiple R&D and innovation centers in Beijing, Shanghai, Nanjing, Lianyungang, as well as in Europe and North America, with a global R&D team of over 2,900 people. We adhere to the concept of openness and win-win cooperation, striving to become a world-leading pharmaceutical enterprise. Through measures such as in-house innovation, major business development (BD) deals, international cooperation, and M&A, we actively supplement our innovation pipeline and technology platforms. At the same time, we connect extensively with renowned research institutions and scientific institutes at home and abroad, gathering global innovation resources to expand our international influence.
By the end of 2025, the company will have a cumulative total of 21 innovative products approved for marketing; in the next three years, more than ten innovative products are expected to enter the marketing stage. We look forward to bringing more and better medication options to patients as an increasing number of high-quality products enter their intensive harvest period, warming more lives with healthy technology.
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0 %+R&D Personnel Hold a Master's Degree or Higher
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0 +Innovative drug projects in the pipeline
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0 +National Science and Technology Major Projects for
"Innovative Drug Research and Development" undertaken -
0 +Patents Granted Cumulatively
TECHNOLOGY INNOVATION
RESEARCHING PIPELINE
100
All
9
Preclinical
22
Phase I
21
Phase II
23
Phase III/Pivotal Clinical
25
Marketing Application
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Oncology
-
Respiratory
-
Hepatology
Metabolism -
Surgery
Analgesic
- Innovative Drug
- Biosimilar
Generic Drug
- Phase I
- Phase II
- Phase III
- Marketing Application
- BE Study
- Phase I
- Pivotal Clinical
- Marketing Application
| Product | Target/Mechanism of Action | Drug Type | Indication | IIIIIIMarketing Application |
|---|---|---|---|---|
| TQB3616 | CDK2/4/6 inhibitor | Small molecule | HR+/HER2- breast cancer | |
| TQ05105 | JAK/ROCK inhibitor | Small molecule | Myelofibrosis, graft versus host disease, hemophagocytic syndrome | |
| AL2846 | AXL/MET tyrosine kinase inhibitor | Small molecule | Non-small cell lung cancer, differentiated thyroid cancer | |
| TQB3454 | IDH1 inhibitor | Small molecule | Advanced biliary tract cancer with IDH1 mutation | |
| TQB2102 | HER2 bispecific ADC | Large molecule | Breast cancer, non-small cell lung cancer, biliary tract cancer, colorectal cancer, gastric cancer, and other advanced malignant neoplasm | |
| M701 | CD3/EpCAM bispecific antibody | Large molecule | Malignant ascites, malignant pleural effusion | |
| TQB3473 | SYK inhibitor | Small molecule | Primary immune thrombocytopenia | |
| FHND9041 | EGFR inhibitor (3rd generation) | Small molecule | Non-small cell lung cancer | |
| TQB3909 | BCL-2 inhibitor | Small molecule | Chronic lymphocytic leukaemia/small lymphocytic lymphoma, acute myeloid leukaemia, acute lymphocytic leukaemia, etc. | |
| LM-108 | CCR8 monoclonal antibody | Large molecule | Advanced malignant neoplasm | |
| TQB2868 | Anti-PD-1/TGF-β bifunctional fusion protein | Large molecule | Pancreas cancer | |
| TQB2930 | HER2 bispecific antibody | Large molecule | Breast cancer, gastric cancer | |
| TQB2916 | CD40 agonistic monoclonal antibody | Large molecule | Advanced malignant neoplasm | |
| TQB2928 | CD47 monoclonal antibody | Large molecule | Bone sarcoma | |
| TQB3702 | BTK inhibitor | Small molecule | Relapsed/refractory advanced hematologic malignancies | |
| TQB3617 | BET inhibitor | Small molecule | Myelofibrosis | |
| TQB3915 | Selective estrogen receptor covalent antagonist (SERCA) | Small molecule | HR+/HER2- breast cancer | |
| TQB2825 | CD20/CD3 bispecific antibody | Large molecule | Follicular lymphoma, diffuse large B-cell lymphoma, mantle cell lymphoma | |
| FHND6091 | Proteasome inhibitor | Small molecule | Multiple myeloma, biliary tract cancer, lupus erythematosus | |
| FHND5071 | RET inhibitor | Small molecule | Solid tumor | |
| NTQ1062 | AKT inhibitor | Small molecule | Solid tumor | |
| TQB3720 | Androgen receptor (AR) antagonist | Small molecule | Prostate cancer | |
| TQB2103 | Claudin18.2 ADC | Large molecule | Advanced malignant neoplasm | |
| TQB2934 | BCMA/CD3 bispecific antibody | Large molecule | Multiple myeloma | |
| TQB3912 | AKT inhibitor | Small molecule | Advanced malignant neoplasm | |
| TQB2922 | EGFR/cMET bispecific antibody | Large molecule | Advanced malignant neoplasm | |
| TQB3006 | SOS1 inhibitor | Small molecule | Advanced malignant neoplasm | |
| TQB3107 | XPO1 inhibitor | Small molecule | Lymphoma, leukaemia, and various solid tumors | |
| TQB3117 | ATM inhibitor | Small molecule | Advanced malignant neoplasm | |
| TQB3911 | BCR-ABL1 tyrosine kinase inhibitor | Small molecule | Hematological malignancy | |
| TQB3002 | EGFR inhibitor (4th generation) | Small molecule | Advanced malignant neoplasm | |
| TQB2029 | GPRC5D/CD3 bispecific antibody | Large molecule | Multiple myeloma | |
| TQB2252 | PD-1/LAG-3 combination | Large molecule | Advanced malignant neoplasm | |
| TCC1727 | Selective ATR inhibitor | Small molecule | Advanced malignant neoplasm | |
| NTQ3617 | MAT2A inhibitor | Small molecule | Advanced malignant neoplasm | |
| TQH2722 | IL-4Rα monoclonal antibody | Large molecule | Chronic sinusitis with/without nasal polyps, atopic dermatitis, seasonal allergic rhinitis | |
| TQC2731 | TSLP monoclonal antibody | Large molecule | Severe asthma, chronic sinusitis with nasal polyps, chronic obstructive pulmonary disease (COPD) | |
| TQC3721 | PDE3/4 inhibitor | Small molecule | Chronic obstructive pulmonary disease (COPD) | |
| TQC2938 | ST2 monoclonal antibody | Large molecule | Asthma, chronic obstructive pulmonary disease (COPD) | |
| TDI01 | ROCK2 inhibitor | Small molecule | Idiopathic pulmonary fibrosis (IPF), graft-versus-host disease (GVHD) | |
| CPX102 | Type III interferon (IL-29) | Large molecule | Respiratory syncytial virus (RSV) infection | |
| TCR1672 | P2X3 antagonist | Small molecule | Refractory chronic cough | |
| TQC3927 | MABA dual target | Small molecule | Chronic obstructive pulmonary disease (COPD) | |
| TQD3524 | Polymyxin E2 | Small molecule | Carbapenem-resistant organism (CRO) infection | |
| TQD3606 | Meropenem and avibactam sodium | Small molecule | Carbapenem-resistant organism (CRO) infection | |
| TQC3301 | Budesonide inhalation spray | Small molecule | Asthma | |
| Lanifibranor | Pan-PPAR agonist | Small molecule | Metabolic dysfunction-associated steatohepatitis (MASH) | |
| TQA2225 | FGF21 fusion protein | Large molecule | Metabolic dysfunction-associated steatohepatitis (MASH) | |
| TQ-A3334 | TLR-7 agonist | Small molecule | Hepatitis B | |
| TQA3810 | TLR-8 agonist | Small molecule | Hepatitis B | |
| TQA3605 | HBV capsid assembly modulator (CAM) | Small molecule | Hepatitis B | |
| TQA3038 | siRNA | Small molecule | Hepatitis B | |
| CPX101 | GIPR antagonist/GLP-1R agonist | Large molecule | Weight loss | |
| PL-5 | Antimicrobial peptide | Category 1 new drug | Secondary wound infection | |
| QP001 | Meloxicam injection (COX-2 inhibitor) | Category 2 new drug | Postoperative analgesia in adults | |
| Naldemedine | Peripherally acting μ-opioid receptor antagonist | Category 1 new drug | Opioid-induced constipation | |
| TRD205 | AT2R antagonist | Category 1 new drug | Neuropathic pain | |
| TRD303 | Ropivacaine extended-release solution (local anesthetic) | Category 2 new drug | Postoperative analgesia | |
| YMP | Dexmedetomidine transdermal patch (α2-adrenergic receptor agonist) | Category 2 new drug | Perioperative insomnia |
| Product | Indication | BE StudyPhase IPivotal ClinicalMarketing Application |
|---|---|---|
| Degarelix acetate for injection | Advanced prostate cancer | |
| Enzalutamide soft capsules | Prostate cancer | |
| Ruxolitinib tablets | Myelofibrosis | |
| Ibrutinib capsules | Mantle cell lymphoma, chronic lymphocytic leukaemia, etc. | |
| Pamidronate disodium injection | Neoplasm bone metastasis | |
| Apalutamide tablets | Prostate cancer | |
| Nelarabine injection | Lymphocytic leukaemia, lymphoma | |
| Abiraterone acetate tablets (II) | Prostate cancer | |
| Daratumumab injection | Multiple myeloma | |
| Netupitant and palonosetron capsules | Chemotherapy-induced vomiting | |
| Ixazomib citrate capsules | Multiple myeloma | |
| Relugolix tablets | Prostate cancer | |
| Chidamide tablets | Breast cancer, diffuse large B-cell lymphoma, etc. | |
| Tedizolid phosphate for injection | Antibacterial | |
| Umeclidinium and vilanterol inhalation powder | Chronic obstructive pulmonary disease (COPD) | |
| Tiotropium bromide inhalation powder | Chronic obstructive pulmonary disease (COPD) | |
| Amphotericin B liposome for injection | Deep fungal infection | |
| Posaconazole injection | Antifungal | |
| Procaterol hydrochloride granules | Bronchodilator | |
| Arformoterol tartrate solution for nebulization | Chronic obstructive pulmonary disease (COPD) | |
| Bromhexine hydrochloride solution for inhalation | Patients with difficulty expectorating sputum due to chronic bronchitis, asthma, etc. | |
| Mepolizumab injection | Asthma, chronic sinusitis with nasal polyps | |
| Delamanid tablets | Multidrug-resistant pulmonary tuberculosis | |
| Fluticasone furoate and vilanterol inhalation powder | Asthma, chronic obstructive pulmonary disease (COPD) | |
| Salmeterol and fluticasone inhalation powder | Asthma | |
| Beraprost sodium sustained-release tablets | Primary pulmonary arterial hypertension, pulmonary arterial hypertension complicated by scleroderma | |
| Obeticholic acid tablets | Primary biliary cholangitis | |
| Saxagliptin and metformin hydrochloride extended-release tablets | Type 2 diabetes mellitus | |
| Empagliflozin and metformin hydrochloride extended-release tablets | Type 2 diabetes mellitus | |
| Insulin degludec injection | Type 2 diabetes mellitus | |
| Semaglutide injection | Type 2 diabetes mellitus, weight loss | |
| Insulin degludec and liraglutide injection | Type 2 diabetes mellitus | |
| Empagliflozin, linagliptin, and metformin hydrochloride extended-release tablets | Type 2 diabetes mellitus | |
| Recombinant human coagulation factor VIIa for injection | Hemorrhagic disorder | |
| Eldecalcitol soft capsules | Osteoporosis | |
| Flurbiprofen patch (2nd generation) | Analgesia and anti-inflammation for the following diseases and symptoms: osteoarthritis, scapulohumeral periarthritis, myalgia, swelling and pain due to trauma, etc. | |
| Mirogabalin tablets | Neuralgia | |
| Methocarbamol injection | Adjunctive therapy for acute musculoskeletal pain or discomfort | |
| Risedronate sodium tablets | Treatment and prevention of osteoporosis in postmenopausal women | |
| Pregabalin extended-release tablets | Diabetic peripheral neuropathic pain (DPNP) | |
| Elagolix sodium tablets | Endometriosis related pain |
No data available
